Begin by washing and cutting the cauliflower into bite-sized florets.
In a mixing bowl, combine the flour, water, garlic powder, onion powder, salt, and black pepper to create a batter.
Add the cauliflower florets to the bowl and toss until they are well coated in the batter.
Preheat your air fryer to 400°F (200°C) for about 5 minutes.
Lightly spray the air fryer basket with cooking spray or brush with olive oil to prevent sticking.
Place the battered cauliflower florets in the air fryer basket in a single layer, making sure not to overcrowd them.
Air fry the cauliflower at 400°F (200°C) for 15-20 minutes, shaking the basket halfway through to ensure even cooking.
Once the cauliflower is crispy and golden brown, remove it from the air fryer.
In a clean mixing bowl, toss the cooked cauliflower with the buffalo sauce until evenly coated.
Return the cauliflower to the air fryer for an additional 2-3 minutes to set the sauce.
Serve hot with your favorite dipping sauce, such as ranch or blue cheese dressing.